Huang, Y. Get the latest science news in your RSS reader with ScienceDaily's hourly updated newsfeeds, covering hundreds of topics: Keep up to date with the latest news from ScienceDaily via social networks: Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Her YouTube channel is dedicated to data and computer science, including how to educate yourself in these topics. Posth, C. et al. Hi, my name is Tina and I'm a data scientist at a FAANG company. Author pages are created from data sourced from our academic publisher partnerships and public sources. This derived ancestrythe Fournol clustersurvived during the LGM in Solutrean-associated individuals, possibly within the Franco-Cantabrian climatic refugium25, leading to later populations associated with the Magdalenian culture (GoyetQ2 cluster and El Mirn). L. Sineo, M.L. In addition to her rich experience, including bioinformatics cancer research at OICR, Tina is a . Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. Individuals and groups are plotted with the same colours and symbols as in Fig. The baseline of each population was determined using the average heterozygosity rate of individuals estimated from pseudo-diploid genotypes (Supplementary Data 1.E). Currently use of the word 'vape' now means "to inhale and exhale the vapor produced by an . 39, msac017 (2022). 1999 - 20001 year. Data mining is the process of finding patterns in large amounts of data. View Tina Huang's profile on LinkedIn, the world's largest professional community. Nat. Ace the SQL part of any data science job interview and get hired. My name is Tina Huang and Im a data scientist at a FAANG company. Genetic ancestry changes in Stone to Bronze Age transition in the East European plain. a, Geographic locations of newly reported individuals (filled symbols with black outline) and representative previously published individuals (outlined stars). 5 and Supplementary Information, section9). Here, we report genomic data from 4 individuals, including 3 approximately 13,000-year-old genomes from northeastern Italy (Pradis 1), northwestern Italy (Arene Candide 16) and Sicily (San Teodoro 2), as well as increased genome-wide coverage from Tagliente 215 dated to 17ka. Sci. For the placement of individuals onto a Y-chromosomal phylogenetic tree (Extended Data Fig. Rev. I have an undergraduate degree in pharmacology from the University of Toronto. and J.Krause performed or supervised genetic analyses. Fifth, the Oberkassel ancestry in western and central Europe and the Sidelkino ancestry in eastern Europe remained largely isolated for almost 6,000 years until genetic interactions were first observedaround 8ka in northeastern Germany, possibly associated with cultural exchanges along the Baltics49 and around 7.5ka in the upper Volga region, possibly linked to the spread of pottery in the region50. 40, e3 (2012). "Ice Age survivors." Besides, the nucleolus is involved in a variety of cellular functions including cell cycle regulation and cellular stress response. Extensive farming in Estonia started through a sex-biased migration from the steppe. Do you agree to our cookie policy? When Gravettian-associated individuals are included in an admixture graph also featuring Kostenki 14, we find that Fournol 85 fits best as a sister lineage of Goyet Q116-1, whereas the Vstonice group is modelled as a mixture between a lineage related to the Sunghir group and one related to the Goyet Q116-1Fournol 85 branch (Fig. 3,528. Tina Huang Profile page. Open access funding provided by Max Planck Society. de Lige, 2021). 6, eaaz5344 (2020). Connect with them: Email: hellotinah@gmail.com. In addition to her data science work, Tina has also created the popular popular game Code Wars. In panel a, genetic affinity between different ancestries is indicated by thick lines or shades, while admixture is indicated with arrows. Both newly sequenced genomes from Solutrean-associated individuals (Le Piage II (23ka) from southwestern France and La Riera (level 14, 21ka) from northern Spain) show a generalized affinity with members of the Fournol and GoyetQ2 clusters in outgroup f3-statistics (Supplementary Data 2.A). The idea of data warehousing is to store large amounts of data in a way that makes it easier to extract and analyse. A dashed line of 50 cM total ROH is drawn in each panel to help comparison between panels with different y-axis scales. Google Scholar. First Name Tina. 8 Changes of Sidelkino and Oberkassel ancestry proportions in post-14 ka hunter-gatherers. Subsequently, I worked in bioinformatics for a year and then did my Master's in computer science (MCIT) at the University of Pennsylvania. How to Rock at Data Science with Tina Huang, Older: Daily Habit #8: Math or Computer Science Exercise . The genomic history of southeastern Europe. Lcuyer, C., Hillaire-Marcel, C., Burke, A., Julien, M. A. Soonafter8 ka, Sidelkino ancestry was absent in eastern Spain but it had already reached northern Iberia alongside an increase in Oberkassel ancestry (Fig. Curr. Slider with three articles shown per slide. CNRS, MNHN, Universit de Paris Cit, Muse de lHomme, Paris, France, PALEVOPRIM Lab UMR 7262 CNRS-INEE, University of Poitiers, Poitiers, France, Centre de Valorisation des Collections Scientifiques, Universit de Poitiers, Mignaloux Beauvoir, France, Muses de PoitiersVille de Poitiers, Poitiers, France, Departamento de Geologa, Facultad de Ciencia y Tecnologa, Universidad del Pas Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), Leioa, Spain, Sociedad de Ciencias Aranzadi, Donostia-San Sebastian, Spain, Centro UCM-ISCIII de Investigacin sobre Evolucin y Comportamiento Humanos, Madrid, Spain, Institute of Archaeology, University of Rzeszw, Rzeszw, Poland, Foundation for Rzeszw Archaeological Centre, Rzeszw, Poland, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA, Department of Psychiatry, Harvard Medical School, Boston, MA, USA, Groninger Instituut voor Archeologie, Groningen University, Groningen, The Netherlands, Institute of Archaeology and Ethnology, Polish Academy of Science, Pozna, Poland, Institute of History, Archaeology and Ethnography, Dushanbe, Tajikistan, ArchaeoZOOlogy in Siberia and Central AsiaZooSCAn, CNRSIAET SB RAS International Research Laboratory, IRL 2013, Institute of Archaeology SB RAS, Novosibirsk, Russia, Research Institute and Museum of Anthropology, Moscow State University, Moscow, Russia, Grupo de I+D+i EVOADAPTA (Evolucin Humana y Adaptaciones durante la Prehistoria) Departamento de Ciencias Histricas, Universidad de Cantabria, Santander, Spain, Borja Gonzlez-Rabanal,Ana B. Marn-Arroyo&Lawrence G. Straus, Instituto Internacional de Investigaciones Prehistricas de Cantabria (IIIPC), Universidad de Cantabria-Gobierno de Cantabria-Banco Santander, Santander, Spain, Departamento de Biologa de Organismos y Sistemas, Universidad de Oviedo, Oviedo, Spain, Quaternary Environments and Humans, OD Earth and History of Life, Royal Belgian Institute of Natural Sciences, Brussels, Belgium, Caroline Polet,Ivan Jadin&Sbastien Villotte, Muses Royaux dArt et dHistoire, Bruxelles, Belgium, Institute of Historical Research, University of Girona, Catalonia, Spain, Joaquim Soler,Neus Coromina&Isaac Ruf, INRAP/UMR 8215 Trajectoires 21, Paris, France, School of Human Evolution and Social Change, Arizona State University, Tempe, AZ, USA, Department of Anthropology, University of New Mexico, Albuquerque, NM, USA, GoArchPal-GoArchon, Viville sous-les-Cotes, France, Archologie & Mnzkabinett, Universalmuseum Joanneum, Graz, Austria, Museum Das Dorf des Welan, Wllersdorf-Steinabrckl, Austria, Department of Humanities, University of Ferrara, Ferrara, Italy, National Museum of Antiquities, Leiden, The Netherlands, Faculty of Archaeology, Leiden University, Leiden, The Netherlands, Biogeology, Department of Geosciences, University of Tbingen, Tbingen, Germany, Unit de Recherches Art, Archologie Patrimoine, Universit de Lige, Lige, Belgium, I.U. Join a growing community of 11K+ to find accountability partners, take part in productivity sprints, and join discord only events! They, along with it, will be accessible to you indefinitely. 6 Reasons We Just Cant Stop. Sci. No, there are no prerequisites for enrolling. & Zimmermann, A. Save my name, email, and website in this browser for the next time I comment. The key areas to focus on when getting started in data science [6:01] Tina's five steps to consistently doing anything [11:55] Tina's day-to-day life as a data scientist at one of the world's largest tech companies [20:02] How Tina's computer science background helps her work [26:20] Traditional banking culture vs big tech [32:12] Y.H. 38. Created by DataSciencePR. CAS Wren, C. D. & Burke, A. Habitat suitability and the genetic structure of human populations during the Last Glacial Maximum (LGM) in Western Europe. 9) and testing the relative affinity among them using f4-statistics in the form f4(Mbuti, Epigravettian A; Epigravettian B, Epigravettian C) (Supplementary Data 2.E). In panel b, the colour code does not imply archaeological similarities. Science 346, 11131118 (2014). I'm interested in tech, trading, and how to minimize effort and maximize outcome. Tina Huang: Data science, computer science, and career advice expert. What is Marimekko Chart in Data Visualization? . YOUTH VAPING: AN ANALYSIS OF AN EPIDEMIC 6 Youth Vaping: An Analysis of an Epidemic 'Vape.' In the 1980s, this was a phrase used to describe weapon uselimited primarily to science fiction writing. & Steinrcken, M. Parental relatedness through time revealed by runs of homozygosity in ancient DNA. 2b). I hope youve enjoyed reading this article. The competition is based on a pretty strict data set thats been collected by the Stanford Computer Science department. Basically, you minimize effort and maximize outcomes. For individual heterozygosity calculation, we also called pseudo-diploid genotypes from each library, using pileupCaller 1.4.0.3 under random diploid calling mode and the same strategy for different types of libraries as pseudo-haploid genotype calling. Article Sign In Create Free Account. Further north and east, individuals from the Baltics (Baltic HG), Scandinavia (SHG), the Balkans (Iron GatesHG) and Ukraine (Ukraine HG) already carried an Oberkassel/Sidelkino admixed ancestry38,40 before 8ka. 35, 15471549 (2018). Tina Huang is one of the top three students to show up to compete. Opin. Biol. In the MDS plot, the Le Piage II individual falls particularly close to individuals belonging to the Fournol cluster, suggesting a local genetic continuity of this ancestry during the LGM (Supplementary Fig. 8). Tina Huang, a data scientist currently working at a FAANG (Facebook, Amazon, Apple, Netflix, and Google Alphabet) company. We provide a systematic description of the genomic transformations that hunter-gatherer groups experienced from the early Upper Palaeolithic onwards across western and central Eurasia and how those are possibly linked to cultural and climatic changes. Follow Author. Ringbauer, H., Novembre, J. The dates were calibrated using OxCal 4.452 with calibration curve IntCal20 at 95.4% probability53 and when multiple dates were available for the same individual we used the function R_Combine to combine them52. 537, 2432 (2020). Bioinformatics 38, 37683777 (2022). Moreover, none of the Epigravettian-associated individuals have more affinity to southern European than to central-eastern European Gravettian-associated groups, as shown by f4(Mbuti, Epigravettian-associated individual/group; Vstonice, Paglicci 12) that is consistent with 0 (Supplementary Data 2.G). For phylogenetic reconstruction (Extended Data Fig. The genomic similarity of the Oberkassel cluster to Arene Candide 16 in northwestern Italy might imply that Epigravettian-associated ancestry spread from the south to central Europe passing through the western side of the Alpine region. Commun. In central-western Europe, Gravettian-associated individuals from Goyet show affinity to both clusters. As recommended, we analysed individuals with over 400,000 SNPs called on the 1240k panel101 and we called ROH longer than 4cM (Supplementary Data 3.B). Low latency, reasonably low communication overhead and ability to support real time applications are the reasons for . Required fields are marked *. 27 and 28 and Supplementary Data 3.G. Hi! These results show that some, but not all, of the genomic ancestries present in Europe between around 40ka and 30ka survived in the Gravettian-associated populations studied so far. Villalba-Mouco, V. et al. Even better your perks will stay yours even after you complete the course. You have to deal with large datasets; however, you have to do your work in a way that makes sense to your team. Known to have been the coldest phase of the last Ice Age, the LGM is considered to have caused a demographic decline in large parts of Europe10, with populations retracting to southern latitudes as attestedfor exampleby the contemporaneity of the Solutrean culture (2419ka) in the Iberian peninsula and southern France. In the video above, she explains the two major components of big data: data warehousing and data science. Genomic insights into the origin of farming in the ancient Near East. Gronenborn, D. in The Spread of the Neolithic to Central Europe (RGZM, 2010). Wyprodukowany w konwencji anime serial stanowi spin-off produkcji "Midzy nami, Misiami", ktrej reyserem wykonawczym . It encourages me to go out and re-learn SQL and excites me for the mock interviews to come. 7 Admixture dates between Oberkassel/Villabruna and ANE ancestries in the oldest individuals from the Sidelkino cluster. Hajdinjak, M. et al. The authors thank G. Marciani and O. Jris for comments on archaeology; C. Jeong, M. Spyrou and K. Prfer for comments on genetics; M. OReilly for graphical support for Fig. Previously, she has interned at Goldman Sachs where she used Python and Scala to implement machine learning techniques for automated anomaly detection. Shes also the creator of the Microsoft Excel spreadsheet Data Mining 101. She has also published a book titled Data Science: Principles and Practices which she wrote with co-author Dan Ariely. This is also supported by f4-statistics of the form f4(Mbuti, Fournol 85; Sunghir, test), which are significantly positive for all the individuals included in the Vstonice cluster (Supplementary Data 2.B). Tina Huang Data Scientist. I help students become independent data scientists who are not just good at data analysis, but are also able to think about their own learning and the world around them. Natl Acad. Instead, for the two SNPs associated with skin colour (SLC24A5 (rs1426654) and SLC45A2 (rs16891982)), Sidelkino clusterand Ukraine HG groups show a higher frequency (>90% for SLC24A5 and 2961% for SLC45A2) of the derived alleles related to light skin colour, compared with Oberkassel and Villabruna clusters, where those alleles are almost completely absent (<1%). PubMed 25, 459466 (2015). Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers. The analysed individuals span from the Upper Palaeolithic to the Neolithic. I hold a Bachelors degree at the University of Toronto where I studied pharmacology. From at least 14,000 years ago, an ancestry related to this culture spread from the south across the rest of Europe, largely replacing the Magdalenian-associated gene pool. We were also told that her project was one of the first student projects that has been accepted into a top-tier universitys student programming competition. Dismiss. The genetic prehistory of the Baltic Sea region. The aligned sequences of all individuals with new genomic data reported in this study are available at the European Nucleotide Archive (ENA) under study accession number PRJEB51862. Taiwan. We further validated the genetic distinction between the Vstonice and Fournol clusters observed in the MDS plot with a series of f4-statistics (Supplementary Data 2.B). A Free Service of Your Local Public Library and the Pennsylvania Public Libraries Film Center of the State Library of Pennsylvania Touchstone Pictures In celebration of our twentieth animated feature, we invite you to relive with us the story telling magic, the wit, the wisdom, the humor, the understanding of a very special person who gave the world a timeless and universal art form. These data suggest that the genetic ancestries identified in the pre-40ka individuals analysed so far went largely extinct or were assimilated by subsequent expansions1,9. Nat. She graduated with a degree in Computer Science and Applied Math. In this case, the data is being loaded from the MySQL database. In this video @Tina Huang and I go through 5 subscriber submitted resumes and review them. Develped strategies for promoting G-Mark to Taiwan. Hi, my name is Tina and I'm a data scientist at a FAANG company. View Tina_Huang_Resume_i.pdf from HCI 445 at DePaul University. Her first stepping stone into data science was being a research assistant in Bioinformatics. Our knowledge of the genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to the scarceness and poor molecular preservation of human remains from that period3. Quat. Within Sicily, the 14ka Oriente C individual shows higher affinity with the much younger but geographically closer 10ka Uzzo group30 (n=2) than with the almost contemporaneous San Teodoro 2 individual from eastern Sicily. The compiled genotype file used for analyses, including re-genotyped published genomes, has been uploaded at the Edmond Data Repository of the Max Planck Society (https://edmond.mpdl.mpg.de/dataset.xhtml?persistentId=doi:10.17617/3.Y1KJMF). As the coverage for most ancient samples was not sufficient for diploid genotype calling, we counted the reads covering selected phenotypic SNPs on reference or alternative alleles and computed the group-based allele frequencies following a maximum likelihood approach described in Mathieson et al.37. Inconsistent haplogroup assignments were manually verified as indicated24 (Supplementary Data 1.L). PLoS ONE 14, e0217996 (2019). Nat. Dual ancestries and ecologies of the Late Glacial Palaeolithic in Britain. Hi! Metadata information of studied individuals. 771234-PALEoRIDER (to W.H. Gravettian cranial morphology and human group affinities during the European Upper Palaeolithic. YSYS stands for Your Startup, Your Story and is dedicated to connecting diverse people with opportunities in tech.. The ancient human specimens analysed in this work derive from multiple scientific collaborations. Human bones and teeth were sampled in clean room facilities to minimize the inclusion of modern human DNA contamination during this procedure. Tina Huang is a recent graduate of Stanford. Tina Llorca CPA, CWP, CEPP, CIS, MDRT Expand search. Li, H. et al. This might have been in part triggered by the concomitant expansion of Neolithic farmers across Europe and/or by environmental factors, such as the climatic event around 8.2ka, the largest abrupt cooling in the northern hemisphere during the Holocene epoch46,47. Youll be surprised how much value there is in a quick XGBoost model, for example. 5b and Supplementary Figs. You also get a peek at Tina's Resume, so I don't think you want to miss out on that. Are you Tina Huang? 62, 3643 (2020). This results in a tree with 57 newly reported and previously published ancient individuals while present-day sequences are collapsed in the major Y-chromosome haplogroups (the most basal lineages are not shown). Showcase your skills and bolster your data science credentials. Amina is a software engineer, who is also an accessibility advocate and content creator. Cosimo Posth, He Yu or Johannes Krause. The hunter-gatherers were grouped based on their geographic origins and dates (Supplementary Information, section5). Proc. Limits of long-term selection against Neandertal introgression. Each bar represents one individual with the ROH grouped in four length categories (grouped by colour). Alexis Bledel. Laplace, G. Essai de Typologie Systmatique (Annali dellUniversit di Ferrara, 1964). Similarly, the SMS spam collection data achieves 99.20% for the validation and 99.10% for testing. OUR UNIVERSITY Our University . PubMed Central ), Science . We only plotted groups with more than two individuals and, for this reason, individuals from the GoyetQ116-1 cluster are included here into the Fournol cluster. The Gravettian from a palaeodemographic point of view. Key, F. M. et al. 3b). Olalde, I. 31, 24842493.e7 (2021). Brace, S. et al. We generated genome-wide sequencing data for 102 newly reported hunter-gatherers, and increased coverage for 14 previously published individuals4. Her YouTube channel is dedicated to data and computer science, including how to educate yourself in these topics. The research team describes a large-scale genetic replacement that may have been caused, in part, by climatic changes that forced people to migrate: "At that time, the climate warmed up quickly and considerably and forests spread across the European continent. Jones, E. R. et al. The previously described Vstonice cluster, including a newly reported 29,000-year-old individual from Paglicci cave (Paglicci 12) in southern Italy, is closely related to the previously published genomes from Sunghir and Kostenki 12 in western Russia, which are dated to 34ka and 32ka, respectively4,23. In anticipation of possible near-term approval from the US Food and Drug Administration for renal denervation, there must be an insistence on longer-term clinical outcomes and safety data. Article We then attempted to model 250 published and newly reported hunter-gatherers dated to 145ka using qpAdm as a mixture of Oberkassel, Sidelkino, GoyetQ2 ancestries, and an ancestry maximized in Anatolian Neolithic farmers (ANF), as a considerable portion of the sequenced hunter-gatherer genomes date after around 8ka, when ANF ancestry started spreading across Europe. USA 110, 1575863 (2013). Extended Data Fig. Google Scholar. HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing. Otte, M.) 105160 (Errance, 2013). This means that you have to set up the database tables to represent the data (which can be done by using the right database design patterns) and then run some SQL queries to extract the data that you need. Jensen, T. Z. T. et al. Gnther, T. et al. 8). Nat. Its not clear if shell compete for a spot on the top 200, but I bet shell be there. Evol. Posth, C., Yu, H., Ghalichi, A. et al. iScience 25, 104244 (2022). Her main topic is AI, exploring how it works and, most interestingly, how we increasingly interact with it in the world. These European regions, therefore, constitute climatic refugia where human populations survived during the LGM. Rev. The average calibrated date is shown, with pie charts indicating the estimated proportion of ancestry for each group or individual. Genomic data have shown that modern humans were present in western Eurasia1,2 at least 45ka. Ontario Institute for Cancer Research Toronto, ON. Extended Data Fig. Antiquity 91, 573588 (2017). Science 344, 747750 (2014). 12, 5425 (2021). Using f4-statistics and qpAdm, we confirm that EHG populations in eastern Europe are a mixture of Villabruna/Oberkassel and ANE ancestries (Supplementary Information, section11 and Supplementary Data 2.K). H. Rougier received support from the College of Social and Behavioral Sciences of CSUN and the CSUN Competition for RSCA Awards. Error bars show 1s.e.m. Science 360, 548552 (2018). By co-analysing previously published data with our newly reported genomes associated with the Magdalenian from La Marche (18ka) and Pincevent (15ka) in western and northern France, respectively, and Maszycka (1816ka) in southern Poland, we confirm that the Goyet Q116-1 ancestry survived in all studied Magdalenian-associated genomes besides in Gravettian and Solutrean-associated individuals from southwestern and western Europe (Fig. . Rohland, N., Glocke, I., Aximu-Petri, A. Tina Huang hellotinah@gmail.com | 123-456-7890 | 1 BeepbeepBoop St. Philadelphia, PA 19104 EDUCATION AND HONORS University of Tina Llorca CPA, CWP, CEPP, CIS, MDRT Ampliar bsqueda. Curr. b, Gravettian-associated individuals form two distinct groups, with central-eastern and southern European individuals as part of the Vstonice cluster and western and southwestern European individuals as part of the Fournol cluster. This Villabruna ancestry(hereafter, Villabruna cluster or ancestry) showed connections to ancient and present-day Near Eastern populations4,16, but the mode and tempo of its expansion into the Italian peninsula remain unexplored.
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